Appearances in Christmas specials
As the main character of Dexter's Laboratory, Dexter naturally has a prominent role in the series' Christmas episode, "Dexter Vs. Santa's Claws". The episode's plot revolves around Dexter's belief that Santa Claus is really just his and Dee Dee's father wearing a costume. When Santa himself shows up, Dexter chases after him in his rocket, eventually taking him down and shaving his beard off, only to find out that Santa is, in fact, not his father in a disguise.
Other Christmas productions
Dexter also guest-starred in the segments produced for A Very Cartoon Cartoon Fridays Holiday Special, a special edition broadcast of Cartoon Cartoon Fridays. In one segment parodying a scene from A Christmas Story, Dexter dares Johnny Bravo to stick his tongue on the frozen TV monitors.